This study discusses how integrating health, behavioral health, and social services through cross-system interventions can enhance client outcomes and community impact. Successful implementation hinges on aligning frontline services and organizational operations among service partners. However, strategies for collaboration across multiple implementation contexts have been underexplored empirically. The research focuses on multi-level collaboration strategies employed in Ohio START, an intervention integrating child welfare and evidence-based behavioral health services for families affected by co-occurring child maltreatment and parental substance use disorders.